Molecular mechanisms and therapeutic perspectives of peroxisome proliferator‐activated receptor α agonists in cardiovascular health and disease
… the ligand-activated transcription factor of a nuclear receptor … cell-tube in streptozotocin-induced
diabetic mice are absent by … -remodeling, anti-inflammatory, and antioxidative effects on …
diabetic mice are absent by … -remodeling, anti-inflammatory, and antioxidative effects on …
Targeting endothelial dysfunction and inflammation
… 4 inhibitors, peroxisome proliferator-activated receptor δ … vascular beneficial, anti-oxidative
and anti-inflammatory in either … RAS inhibitors, PPARδ ligands, GLP-1 elevators and GLP-1 …
and anti-inflammatory in either … RAS inhibitors, PPARδ ligands, GLP-1 elevators and GLP-1 …
PPAR-δ: A key nuclear receptor in vascular function and remodeling
L Xiao, N Wang - Journal of Molecular and Cellular Cardiology, 2022 - Elsevier
… Peroxisome proliferator-activated receptors (PPARs) are … diabetic db/db mice [38],
streptozotocin-induced diabetic rats [39]… while enhanced the expression of anti-inflammatory …
streptozotocin-induced diabetic rats [39]… while enhanced the expression of anti-inflammatory …
[HTML][HTML] … Synthetic PPARƳ Derivative Ameliorates Aorta Injury in Experimental Diabetic Rats Mediated by Activation of miR-126-5p Pi3k/AKT/PDK 1/mTOR Expression
… Peroxisome proliferator-activated receptor PPAR) agonists have … Streptozotocin-Induced
T2D through stimulating local … our results and confirmed the anti-inflammatory and anti-oxidant …
T2D through stimulating local … our results and confirmed the anti-inflammatory and anti-oxidant …
Adding SGLT2 Cotransporter Inhibitor to PPARγ Activator Does Not Provide an Additive Effect in the Management of Diabetes-Induced Vascular Dysfunction
A Cinakova, P Krenek, J Klimas, E Kralova - Pharmacology, 2023 - karger.com
… that activation of peroxisome proliferator-activated receptor-gamma (… A direct anti-inflammatory
effect of dapagliflozin was … enzyme expression in streptozotocin-induced diabetic rat …
effect of dapagliflozin was … enzyme expression in streptozotocin-induced diabetic rat …
C66 and B2brbc Modulate Oxidative Stress, Jnk Activity, and Pancreatic Gene Expression In Rats with Streptozotocin-Induced Diabetes
R Stojchevski, S Velichkovikj, J Bogdanov… - … Streptozotocin-Induced … - papers.ssrn.com
… This study aimed to evaluate the antioxidative and anti-inflammatory … B2BrBC inhibited the
expression of Tnf, 407 probably due to direct … Peroxisome proliferator activated receptor alpha …
expression of Tnf, 407 probably due to direct … Peroxisome proliferator activated receptor alpha …
[HTML][HTML] Impact of the renin–angiotensin system on the endothelium in vascular dementia: Unresolved issues and future perspectives
… memory in a streptozotocin-induced diabetes rat model [24]. … proliferator-activated receptor
α (PPARα) and PPARγ [36,37]. … other hand, holds antioxidant and anti-inflammatory effects in …
α (PPARα) and PPARγ [36,37]. … other hand, holds antioxidant and anti-inflammatory effects in …
[HTML][HTML] Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation
R Scandiffio, F Geddo, E Cottone, G Querio… - Nutrients, 2020 - mdpi.com
… family of peroxisome proliferator-activated receptors (PPARs)… the ligand-activated nuclear
receptor superfamily [10,22,23]. … CB2-mediated BCP anti-inflammatory effects were also …
receptor superfamily [10,22,23]. … CB2-mediated BCP anti-inflammatory effects were also …
The potential roles of chitosan oligosaccharide in prevention of kidney injury in obese and diabetic conditions
P Sutthasupha, A Lungkaphin - Food & function, 2020 - pubs.rsc.org
… accountable for the anti-inflammatory effects of COS. COS acts … , 16,17 inhibiting the
peroxisome proliferator-activated receptor γ (… (PPARs) are ligand-activated transcription factors …
peroxisome proliferator-activated receptor γ (… (PPARs) are ligand-activated transcription factors …
[HTML][HTML] Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19
… anti-inflammatory drugs such as JAK inhibitors, IL-6 inhibitors, TNF-α … profile and has
antioxidant, anti-inflammatory, and immunomodulatory … peroxisome proliferator-activated receptors …
antioxidant, anti-inflammatory, and immunomodulatory … peroxisome proliferator-activated receptors …